Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL3 | P15374 | 2/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825720 | 0.96 | UCHL3 (0.41) | UCHL3RARBHTR1ATSHRGPR3 | |
| SCHEMBL9825864 | 0.95 | UCHL3 (0.40) | UCHL3RARBHTR1ATP53TSHR | |
| SCHEMBL9825402 | 0.92 | ALOX5 (0.39) | UCHL3AKR1C2AKR1C3 | |
| SCHEMBL9825972 | 0.85 | AKR1C3 (0.41) | AKR1C2NPC1RAB9AHPGDMAPK1 | |
| SCHEMBL9825519 | 0.84 | CTSS (0.38) | UCHL3PSMB5SKP2NPC1RAB9A | |
| SCHEMBL9826652 | 0.80 | TLR8 (0.40) | PSMB5GPR3 | |
| SCHEMBL9825219 | 0.79 | GPR3 (0.41) | HTR1ATP53GPR3 | |
| SCHEMBL9825625 | 0.79 | GPR3 (0.41) | HTR1ATP53GPR3 | |
| SCHEMBL9824789 | 0.79 | RARB (0.44) | NPC1RAB9ARARBHTR1ATP53 | |
| SCHEMBL3669327 | 0.77 | UCHL3 (0.60) | UCHL3AKR1C2AKR1C1HPGDRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |