Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL3 | P15374 | 2/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825864 | 0.99 | UCHL3 (0.40) | UCHL3GPR3RARBHTR2ATSHR | |
| SCHEMBL9825318 | 0.96 | UCHL3 (0.44) | UCHL3GPR3RARBTSHRHTR1A | |
| SCHEMBL9825402 | 0.90 | ALOX5 (0.39) | UCHL3 | |
| SCHEMBL9825972 | 0.84 | AKR1C3 (0.41) | TSHRHSD17B10PTGS2 | |
| SCHEMBL9826652 | 0.84 | TLR8 (0.40) | GPR3HTR2AHSD11B1TLR8 | |
| SCHEMBL9824789 | 0.83 | RARB (0.44) | GPR3RARBHTR2ATSHRHSD17B10 | |
| SCHEMBL9825219 | 0.83 | GPR3 (0.41) | GPR3HTR2ATLR8HSD17B10HTR1A | |
| SCHEMBL9825625 | 0.83 | GPR3 (0.41) | GPR3HTR2ATLR8HSD17B10HTR1A | |
| SCHEMBL9826442 | 0.80 | GPR3 (0.48) | GPR3HTR2AHSD11B1TLR8 | |
| SCHEMBL9825519 | 0.80 | CTSS (0.38) | UCHL3GPR3HTR2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |