SCHEMBL9825519

SCHEMBL9825519

CCCCc1ccc2cc3cc(C(C)C)cccc-3c2c1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38
PSMB5 P28074 1/20 0.37
TLR8 Q9NR97 1/20 0.36
BCHE P06276 2/20 0.35
UCHL3 P15374 2/20 0.35
GPR3 P46089 1/20 0.35
SKP2 Q13309 1/20 0.34
APLNR P35414 1/20 0.34
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9826652 0.96 TLR8 (0.40) CTSSCTSKPSMB5TLR8BCHE
SCHEMBL9825219 0.95 GPR3 (0.41) CTSSCTSKTLR8GPR3HTR2A
SCHEMBL9825625 0.95 GPR3 (0.41) CTSSCTSKTLR8GPR3HTR2A
SCHEMBL9825454 0.92 CTSS (0.41) CTSSCTSKTLR8HTR2A
SCHEMBL9825167 0.86 CYP1A2 (0.42) CTSSCTSKNPC1HPGDMAPK1
SCHEMBL9825318 0.84 UCHL3 (0.44) PSMB5UCHL3GPR3SKP2NPC1
SCHEMBL9825720 0.80 UCHL3 (0.41) TLR8UCHL3GPR3HTR2A
SCHEMBL9825864 0.79 UCHL3 (0.40) UCHL3GPR3HTR2A
SCHEMBL9875623 0.78 UCHL3 (0.43) CTSSCTSKPSMB5UCHL3GPR3
SCHEMBL9826316 0.78 ALDH1A1 (0.36) BCHEUCHL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037575-A Photostability MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1991-08-06 US disclosed
EP-0187015-B1 SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME MITSUBISHI KASEI CORPORATION (JP) 1991-05-29 EP disclosed