Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.40 |
| ▸ | XDH | P47989 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874691 | 0.88 | NPC1 (0.42) | SLC22A12XDHHPGDALDH1A1HSD17B10 | |
| SCHEMBL891238 | 0.83 | GPR55 (0.41) | HPGDALDH1A1BCL2L1HSD17B10GPR55 | |
| SCHEMBL9826687 | 0.79 | RAB9A (0.50) | HPGDALDH1A1HSD17B10CASP3SENP7 | |
| SCHEMBL9825170 | 0.78 | NPC1 (0.42) | SLC22A12XDHHPGDALDH1A1HSD17B10 | |
| SCHEMBL26184965 | 0.77 | MAPT (0.38) | SLC22A12XDHHPGDALDH1A1HSD17B10 | |
| SCHEMBL24897184 | 0.76 | XDH (0.40) | SLC22A12XDHBACE1HPGDALDH1A1 | |
| SCHEMBL9824769 | 0.75 | RXRA (0.40) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL22891138 | 0.74 | ALDH1A1 (0.35) | ALDH1A1HSD17B10CHUKESR2NPC1 | |
| SCHEMBL21118646 | 0.74 | MAPT (0.46) | BACE1HPGDALDH1A1HSD17B10NPC1 | |
| SCHEMBL20871321 | 0.74 | MAOA (0.43) | ALDH1A1ESR2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0187015-A2 | Squarilium compound and liquid crystal composition containing the same | MITSUBISHI KASEI CORPORATION (JP) | 1986-07-09 | — | — | EP | disclosed |