Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22576567 | 0.78 | SIGMAR1 (0.33) | SMN1; SMN2MAPTPOLB | |
| SCHEMBL26921892 | 0.77 | MAPT (0.30) | MAPTRAB9A | |
| SCHEMBL2891807 | 0.73 | ALDH1A1 (0.43) | SMN1; SMN2MAPTPOLB | |
| SCHEMBL2152620 | 0.72 | PKM (0.48) | POLB | |
| SCHEMBL28003462 | 0.72 | PKM (0.48) | POLB | |
| SCHEMBL23404192 | 0.69 | TOP2A (0.39) | CHRM1MAPT | |
| SCHEMBL28186742 | 0.69 | L3MBTL1 (0.44) | TP53HBBSMN1; SMN2MAPTPOLB | |
| SCHEMBL672209 | 0.69 | ALDH1A1 (0.44) | SMN1; SMN2MAPTPOLB | |
| SCHEMBL9827403 | 0.69 | JAK2 (0.39) | TP53HBBSMN1; SMN2PRMT5WDR77 | |
| SCHEMBL15740398 | 0.69 | DGAT1 (0.32) | MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212558-B1 | A RADIATION SENSITIZER | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-4820844-A | 2-(3'-NITRO-1'-TRIAZOLYL) ACETIC ACID ETHANOL AMIDE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1989-04-11 | — | — | US | disclosed |
| EP-0212558-A2 | A radiation sensitizer | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1987-03-04 | — | — | EP | disclosed |