Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052033 | 0.81 | CCR1 (0.41) | HTTHSD17B10DYRK1A | |
| SCHEMBL26345976 | 0.74 | PDXK (0.34) | — | |
| SCHEMBL28257885 | 0.74 | NOS2 (0.46) | HTTHSD17B10DYRK1A | |
| SCHEMBL29673267 | 0.74 | CCR1 (0.34) | — | |
| SCHEMBL4944670 | 0.74 | CCR1 (0.34) | — | |
| SCHEMBL28822506 | 0.73 | NFE2L2 (0.35) | HTTHSD17B10 | |
| SCHEMBL23074936 | 0.72 | TRPV4 (0.34) | HTTHSD17B10DYRK1A | |
| Ammonia Solution, Strong SCHEMBL28593822 | 0.72 | NOS3 (0.45) | HTTHSD17B10DYRK1A | |
| SCHEMBL16127584 | 0.72 | HTT (0.34) | HTTHSD17B10DYRK1A | |
| SCHEMBL1567878 | 0.71 | NOS3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133612-B1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | MONSANTO COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |