Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922270 | 0.74 | ALDH1A1 (0.50) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL929237 | 0.73 | APP (0.52) | GRM5RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3449895 | 0.71 | ALDH1A1 (0.44) | GRM5RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3150956 | 0.70 | HSD17B10 (0.40) | GRM5RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL29429053 | 0.70 | APP (0.55) | GRM5RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL31026477 | 0.67 | APP (0.34) | GRM5RAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL31026479 | 0.67 | ALDH1A1 (0.46) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3447266 | 0.67 | ALDH1A1 (0.46) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3448582 | 0.66 | ASIC3 (0.44) | GRM5RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3840989 | 0.66 | CYP2A6 (0.49) | GRM5RAB9ANPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11187690-B2 | Synthetic receptors for hydrosulfide | UNIVERSITY OF OREGON (US) | 2021-11-30 | — | — | US | disclosed |
| US-11021447-B2 | Fluorescent halogen bonding arylethynyl scaffolds for anion recognition | UNIVERSITY OF OREGON (US) | 2021-06-01 | — | — | US | disclosed |
| EP-2948430-B1 | PHENYLACETYLENES | UNIV OREGON (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20190345113-A1 | FLUORESCENT HALOGEN BONDING ARYLETHYNYL SCAFFOLDS FOR ANION RECOGNITION | UNIVERSITY OF OREGON (US) | 2019-11-14 | — | — | US | disclosed |
| US-9964531-B2 | Phenylacetylenes | UNIVERSITY OF OREGON (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170350870-A1 | SYNTHETIC RECEPTORS FOR HYDROSULFIDE | UNIVERSITY OF OREGON (US) | 2017-12-07 | — | — | US | disclosed |
| US-20150355153-A1 | PHENYLACETYLENES | UNIVERSITY OF OREGON (US) | 2015-12-10 | — | — | US | disclosed |
| EP-2948430-A1 | PHENYLACETYLENES | University Of Oregon (US) | 2015-12-02 | — | — | EP | disclosed |
| US-8841460-B2 | Tunable phenylacetylene hosts | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2014-09-23 | — | — | US | disclosed |
| WO-2014116578-A1 | PHENYLACETYLENES | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2014-07-31 | — | — | WO | disclosed |
| US-20140031559-A1 | TUNABLE PHENYLACETYLENE HOSTS | State of Oregon, acting by and through the State Board of Higher Education on Behalf of University (US) | 2014-01-30 | — | — | US | disclosed |
| US-20110015396-A1 | TUNABLE PHENYLACETYLENE HOSTS | THE STATE OF OREGON ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2011-01-20 | — | — | US | disclosed |
| US-7803946-B2 | Tunable phenylacetylene hosts | UNIVERSITY OF OREGON | 2010-09-28 | — | — | US | disclosed |
| US-20080167472-A1 | TUNABLE PHENYLACETYLENE HOSTS | STATE OF OREGON ACTING BY AND THROUGH THE STATE | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11187690-B2 | Synthetic receptors for hydrosulfide | OR10J3, OXSR1, HCAR3 | GRM5 379/4885RAB9A 1172/4885MEN1 4731/4885 |
| US-20170350870-A1 | SYNTHETIC RECEPTORS FOR HYDROSULFIDE | OR10J3, OXSR1, HCAR3 | GRM5 379/4885RAB9A 1172/4885MEN1 4731/4885 |
| US-20150355153-A1 | PHENYLACETYLENES | HDAC10, H1-10, H1-0 | GRM5 4345/4885RAB9A 1507/4885MEN1 3213/4885 |
| US-20190345113-A1 | FLUORESCENT HALOGEN BONDING ARYLETHYNYL SCAFFOLDS FOR ANION RECOGNITION | NAA10, SCN10A, NAT10 | GRM5 3014/4885RAB9A 1402/4885MEN1 4548/4885 |
| US-20140031559-A1 | TUNABLE PHENYLACETYLENE HOSTS | NAA10, OR10J3, CBR3 | GRM5 1940/4885RAB9A 1197/4885MEN1 4356/4885 |
| US-20110015396-A1 | TUNABLE PHENYLACETYLENE HOSTS | AADAC, PML, AHR | GRM5 3139/4885RAB9A 2568/4885MEN1 4278/4885 |
| US-20080167472-A1 | TUNABLE PHENYLACETYLENE HOSTS | AADAC, PML, AHR | GRM5 3139/4885RAB9A 2568/4885MEN1 4278/4885 |
| US-11021447-B2 | Fluorescent halogen bonding arylethynyl scaffolds for anion recognition | NAA10, SCN10A, NAT10 | GRM5 3014/4885RAB9A 1402/4885MEN1 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.