Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.40 |
| ▸ | NPC1 | O15118 | 12/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.37 |
| ▸ | RELA | Q04206 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832310 | 0.82 | MAPT (0.40) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL9830880 | 0.81 | CDK5 (0.52) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9830397 | 0.79 | HTR2B (0.45) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL9823352 | 0.79 | TDP1 (0.42) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL9831314 | 0.78 | ALDH1A1 (0.40) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9831082 | 0.77 | CCNA2 (0.49) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9832086 | 0.76 | KDM4E (0.48) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL9829838 | 0.75 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL9829473 | 0.75 | KDM4E (0.42) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL9833230 | 0.75 | DDX3X (0.47) | RAB9ANPC1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |