Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125512 | 0.92 | SYK (0.37) | SYKGCKPTGS1PTGS2GRM5 | |
| SCHEMBL9122090 | 0.87 | ALDH1A1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL9830610 | 0.81 | WNT3A (0.39) | PTGS1PTGS2 | |
| SCHEMBL9123205 | 0.78 | RAB9A (0.41) | — | |
| SCHEMBL9124269 | 0.77 | VCAM1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL9122485 | 0.75 | BACE1 (0.38) | — | |
| SCHEMBL9123927 | 0.75 | MKNK1 (0.39) | — | |
| SCHEMBL9120095 | 0.73 | KDR (0.35) | — | |
| SCHEMBL9120151 | 0.73 | DGAT1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL9123013 | 0.72 | NPC1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425650-A1 | ANTI-INFLAMMATORY 4-AMINOPHENOL DERIVATIVES. | FISONS PLC (GB) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990014338-A1 | ANTI-INFLAMMATORY 4-AMINOPHENOL DERIVATIVES | FISONS PLC (GB) | 1990-11-29 | — | — | WO | disclosed |