Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829749 | 0.82 | DDX3X (0.44) | DDX3XSMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL9830803 | 0.81 | ALDH1A1 (0.62) | SMN1; SMN2HPGDRAB9ANPC1GAA | |
| SCHEMBL9823409 | 0.81 | DDX3X (0.43) | DDX3XSMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL9830987 | 0.76 | GAA (0.54) | SMN1; SMN2HPGDRAB9ANPC1GAA | |
| SCHEMBL10877847 | 0.75 | TDP1 (0.51) | SMN1; SMN2RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL9832642 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDRAB9ANPC1GAA | |
| SCHEMBL10647360 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2HPGDRAB9ANPC1GAA | |
| SCHEMBL9831938 | 0.74 | PPARA (0.49) | SMN1; SMN2HPGDRAB9ANPC1GAA | |
| SCHEMBL9832312 | 0.73 | ROCK1 (0.51) | SMN1; SMN2HPGDRAB9ANPC1GAA | |
| SCHEMBL9829467 | 0.72 | ROCK1 (0.42) | SMN1; SMN2HPGDNPC1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |