Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17107156 | 0.79 | ALDH1A1 (0.79) | KMT2AMEN1ALOX5RAB9ALMNA | |
| SCHEMBL10810440 | 0.78 | ALOX5 (0.76) | KMT2AMEN1ALOX5RAB9ALMNA | |
| SCHEMBL9833422 | 0.77 | ALOX5 (0.50) | KMT2AMEN1ALOX5RAB9ALMNA | |
| SCHEMBL14825142 | 0.77 | KMT2A (1.00) | KMT2AMEN1ALOX5RAB9ALMNA | |
| SCHEMBL15086878 | 0.76 | ALOX5 (0.74) | KMT2AMEN1ALOX5RAB9ALMNA | |
| SCHEMBL9833487 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1RAB9ALMNANPSR1 | |
| SCHEMBL2753568 | 0.76 | ADORA3 (0.73) | KMT2AMEN1ALOX5RAB9ALMNA | |
| SCHEMBL12248914 | 0.76 | ALDH1A1 (0.66) | KMT2AMEN1ALOX5RAB9ALMNA | |
| SCHEMBL31665058 | 0.76 | RAB9A (0.65) | KMT2AMEN1ALOX5RAB9ALMNA | |
| SCHEMBL9829808 | 0.76 | RAB9A (0.58) | KMT2AMEN1RAB9ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |