Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832335 | 0.77 | KMT2A (0.62) | ALOX5MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9830803 | 0.77 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11156635 | 0.74 | CNR2 (0.52) | POLBNPSR1BTK | |
| SCHEMBL9830851 | 0.74 | RARA (0.60) | ALOX5MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL3788576 | 0.73 | POLB (0.55) | MEN1KMT2ALMNAPOLBRAB9A | |
| SCHEMBL11378900 | 0.73 | BTK (0.47) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL151398 | 0.72 | NPC1 (0.50) | MEN1KMT2ACYP1A2CYP2C9RAB9A | |
| SCHEMBL18136486 | 0.72 | ALOX5 (0.61) | ALOX5MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9823477 | 0.72 | TDP1 (0.64) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3308450 | 0.71 | SCN9A (0.57) | ALOX5MEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |