Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.39 |
| ▸ | ADH1C | P00326 | 3/20 | 0.39 |
| ▸ | ADH1A | P07327 | 3/20 | 0.39 |
| ▸ | ADH7 | P40394 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | ADH4 | P08319 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 9/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084862 | 0.85 | ADH1B (0.45) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL14343155 | 0.81 | GNAI3 (0.46) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL10772954 | 0.79 | LMNA (0.43) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL3839686 | 0.79 | ADH1B (0.43) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL19812647 | 0.79 | RRM1 (0.46) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL8804336 | 0.76 | CTSK (0.41) | ADH1BADH1CADH1AADH7CTSK | |
| SCHEMBL27345133 | 0.76 | CTSK (0.44) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL15870345 | 0.76 | EPHX1 (0.43) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL28101675 | 0.75 | ADH1B (0.44) | ADH1BADH1CADH1AADH7EPHX1 | |
| SCHEMBL23677011 | 0.75 | GPR84 (0.46) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |