Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.35 |
| ▸ | TUBB | P07437 | 6/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833168 | 0.83 | L3MBTL1 (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9832757 | 0.82 | TUBB4A (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9799313 | 0.81 | TUBB4A (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9799541 | 0.81 | PTGS2 (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9832379 | 0.79 | NPC1 (0.35) | ALDH1A1HPGDMAPTCYP3A4CYP1A2 | |
| SCHEMBL9833083 | 0.79 | OPRM1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9833650 | 0.78 | MAPT (0.41) | L3MBTL1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9799796 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTCYP3A4MEN1 | |
| SCHEMBL9832269 | 0.70 | MAPT (0.36) | ALDH1A1KDM4EHPGDMAPTCYP3A4 | |
| SCHEMBL9799824 | 0.68 | NPC1 (0.35) | L3MBTL1MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4857543-A | TREATMENT OF GASTROINTESTINAL DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0297782-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |