Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833965 | 0.79 | NAAA (0.41) | ALOX5 | |
| SCHEMBL9832722 | 0.78 | MPO (0.39) | ALDH1A1GLSHDAC1 | |
| SCHEMBL9834514 | 0.77 | HRH1 (0.41) | ALDH1A1 | |
| SCHEMBL9832047 | 0.77 | HRH1 (0.45) | GLSHDAC1HDAC6 | |
| SCHEMBL4008741 | 0.77 | GAA (0.38) | ALDH1A1TDP1CYP3A4ALOX15USP2 | |
| SCHEMBL4382935 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4ALOX15USP2 | |
| SCHEMBL4369185 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4ALOX15USP2 | |
| SCHEMBL5634683 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4ALOX15USP2 | |
| SCHEMBL4379184 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4ALOX15USP2 | |
| SCHEMBL4373147 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4ALOX15USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |