Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832892 | 0.82 | NAAA (0.37) | MPOGLS | |
| SCHEMBL9832047 | 0.80 | HRH1 (0.45) | GLSPARP10HDAC1 | |
| SCHEMBL9834514 | 0.78 | HRH1 (0.41) | ALDH1A1MAPT | |
| SCHEMBL9833192 | 0.78 | ALDH1A1 (0.37) | GLSALDH1A1HDAC1 | |
| SCHEMBL9832110 | 0.77 | TDP1 (0.41) | GLSL3MBTL1 | |
| SCHEMBL9833469 | 0.76 | HDAC1 (0.46) | GLSTAAR1HDAC1DAONR3C2 | |
| SCHEMBL9833331 | 0.76 | HDAC1 (0.47) | TAAR1HDAC1NR3C2 | |
| SCHEMBL9833965 | 0.75 | NAAA (0.41) | HCAR3 | |
| SCHEMBL13492011 | 0.70 | MAPT (0.59) | TAAR1ALDH1A1HDAC1MAPTPTGER1 | |
| SCHEMBL30427741 | 0.70 | MAPT (0.59) | TAAR1ALDH1A1HDAC1MAPTPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |