Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832722 | 0.80 | MPO (0.39) | HDAC1GLSPARP10 | |
| SCHEMBL9834514 | 0.80 | HRH1 (0.41) | HRH1NAAA | |
| SCHEMBL9658041 | 0.78 | SMN1; SMN2 (0.61) | HRH1CYP1A2SMN1; SMN2CYP2C19NAAA | |
| SCHEMBL9833192 | 0.77 | ALDH1A1 (0.37) | HDAC1GLSHDAC6 | |
| SCHEMBL9832110 | 0.76 | TDP1 (0.41) | NAAAGLS | |
| SCHEMBL9832892 | 0.76 | NAAA (0.37) | NAAAGLS | |
| SCHEMBL9833469 | 0.75 | HDAC1 (0.46) | NAAAHDAC1GLSHDAC6 | |
| SCHEMBL7378329 | 0.74 | HRH1 (0.64) | HRH1CYP1A2SMN1; SMN2CYP2C19NAAA | |
| SCHEMBL18248625 | 0.74 | HRH1 (0.64) | HRH1CYP1A2SMN1; SMN2CYP2C19NAAA | |
| SCHEMBL20378876 | 0.73 | SMN1; SMN2 (0.55) | HRH1CYP1A2SMN1; SMN2CYP2C19NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |