Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.30 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834514 | 0.82 | HRH1 (0.41) | NAAACES1NCEH1FAAH | |
| SCHEMBL9832892 | 0.81 | NAAA (0.37) | NAAAFAAH | |
| SCHEMBL9833181 | 0.81 | HDAC3 (0.44) | NAAA | |
| SCHEMBL9832110 | 0.81 | TDP1 (0.41) | NAAAFAAH | |
| SCHEMBL9833192 | 0.79 | ALDH1A1 (0.37) | ALOX5 | |
| SCHEMBL9837576 | 0.79 | ALOX5 (0.46) | ALOX5FAAH | |
| SCHEMBL9833469 | 0.77 | HDAC1 (0.46) | NAAACES1NCEH1 | |
| SCHEMBL9834740 | 0.76 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9832722 | 0.75 | MPO (0.39) | HCAR3 | |
| SCHEMBL9833331 | 0.75 | HDAC1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |