Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987113 | 0.87 | PDK1 (0.49) | TBXAS1KMT2AALDH1A1PDK1MAPT | |
| SCHEMBL9871883 | 0.84 | TBXAS1 (0.51) | TBXAS1ALDH1A1PDK1NPC1RAB9A | |
| SCHEMBL7613074 | 0.72 | KMT2A (0.56) | KMT2ABRD4ALDH1A1MAPT | |
| SCHEMBL9834133 | 0.70 | TBXAS1 (0.78) | TBXAS1ALDH1A1NPC1 | |
| SCHEMBL10439319 | 0.69 | KDM4E (0.45) | KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9834147 | 0.69 | TBXAS1 (0.33) | TBXAS1 | |
| SCHEMBL9835048 | 0.69 | ALDH1A1 (0.32) | KMT2AALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL4432302 | 0.68 | MTNR1A (0.53) | KMT2AALDH1A1 | |
| SCHEMBL29882799 | 0.68 | MTNR1A (0.53) | KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL10812638 | 0.68 | KMT2A (0.38) | KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |