Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 9/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836958 | 0.94 | PDE3B (0.37) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9835458 | 0.82 | PDE4A (0.40) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9835807 | 0.81 | KMO (0.42) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9836532 | 0.79 | PDE3B (0.35) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9834522 | 0.77 | ALDH1A1 (0.42) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9835976 | 0.77 | SMN1; SMN2 (0.47) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9836476 | 0.77 | TDP1 (0.48) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9837594 | 0.73 | PDE3B (0.41) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9836932 | 0.73 | TSHR (0.43) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9837456 | 0.71 | PDE4A (0.39) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238357-B1 | 1,2,4-TRIAZINONE DERIVATIVES, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-29 | — | — | EP | claimed |