Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.67 |
| ▸ | DRD3 | P35462 | 6/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10760285 | 0.96 | DRD2 (0.64) | DRD2DRD3ADRA1BP2RX7SIGMAR1 | |
| SCHEMBL3631349 | 0.94 | DRD2 (0.63) | DRD2DRD3ADRA1BP2RX7SIGMAR1 | |
| SCHEMBL4249527 | 0.90 | DRD3 (0.61) | DRD2DRD3ADRA1BP2RX7SIGMAR1 | |
| SCHEMBL20329228 | 0.86 | DRD3 (0.68) | DRD2DRD3 | |
| SCHEMBL4249388 | 0.83 | LMNA (0.60) | DRD2DRD3ADRA1BP2RX7SIGMAR1 | |
| SCHEMBL27340092 | 0.82 | DRD3 (0.66) | DRD2DRD3 | |
| SCHEMBL9253472 | 0.82 | DRD3 (0.66) | DRD2DRD3 | |
| SCHEMBL10367443 | 0.81 | DRD3 (0.60) | DRD2DRD3 | |
| SCHEMBL9249869 | 0.79 | ACHE (0.68) | DRD2DRD3ADRA1BP2RX7 | |
| SCHEMBL7381976 | 0.79 | DRD2 (0.68) | DRD2DRD3ADRA1BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210782-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
| US-4778796-A | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0210782-A2 | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-02-04 | — | — | EP | disclosed |