Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837332 | 1.00 | PKM (0.43) | PKMHTR1ADRD2DRD3DRD4 | |
| SCHEMBL10558635 | 1.00 | PKM (0.43) | PKMHTR1ADRD2DRD3DRD4 | |
| SCHEMBL9835778 | 1.00 | PKM (0.43) | PKMHTR1ADRD2DRD3DRD4 | |
| SCHEMBL9835784 | 1.00 | PKM (0.43) | PKMHTR1ADRD2DRD3DRD4 | |
| SCHEMBL11220571 | 0.74 | HTR1A (0.45) | HTR1ADRD3DRD4ADRB1HTR1B | |
| SCHEMBL11875374 | 0.71 | HTR2B (0.47) | PKMDRD4HTR2BL3MBTL1GRM2 | |
| SCHEMBL9225971 | 0.71 | PDK1 (0.46) | HTR1ADRD3ADRB1ADRA2ASLC6A2 | |
| SCHEMBL9225959 | 0.71 | PDK1 (0.46) | HTR1ADRD3ADRB1ADRA2ASLC6A2 | |
| SCHEMBL9837429 | 0.70 | HTR1A (0.41) | HTR1ADRD2DRD3DRD4SLC6A4 | |
| SCHEMBL11071694 | 0.70 | PARP1 (0.44) | PKMHTR2BKDM4ERECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251938-B1 | STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF INDOLE DERIVATIVES | SANOFI (FR) | 1991-11-06 | — | — | EP | claimed |