Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.44 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAX | P61244 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834480 | 0.85 | CRHBP (0.70) | CRHBPCRHR2MAPTKMT2AMEN1 | |
| SCHEMBL4205393 | 0.85 | CRHBP (0.70) | CRHBPCRHR2MAPTKMT2AMEN1 | |
| SCHEMBL4214475 | 0.85 | CRHBP (0.70) | CRHBPCRHR2MAPTKMT2AMEN1 | |
| SCHEMBL7325216 | 0.79 | MPO (0.83) | MPOGRIK1MAPTKMT2AMEN1 | |
| SCHEMBL9838079 | 0.78 | MAPT (0.58) | CRHBPCRHR2MAPTKMT2AMEN1 | |
| SCHEMBL17434401 | 0.76 | MAPT (0.70) | MAPTKMT2AMEN1CTSVCTSL | |
| SCHEMBL1463066 | 0.76 | GRIK1 (0.84) | MPOGRIK1MAPTKMT2AMEN1 | |
| SCHEMBL4211539 | 0.76 | MAPT (0.72) | MPOGRIK1MAPTKMT2AMEN1 | |
| SCHEMBL9837846 | 0.76 | CTSV (0.56) | CRHBPCRHR2MAPTKMT2AMEN1 | |
| SCHEMBL9835884 | 0.76 | CTSV (0.67) | CRHBPCRHR2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994493-A | Treatment of cerebral edema | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN (DE) | 1991-02-19 | — | — | US | disclosed |