Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837596 | 0.98 | NFE2L2 (0.36) | NFE2L2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL9837533 | 0.76 | EPHX1 (0.38) | NFE2L2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL9837839 | 0.75 | NFE2L2 (0.47) | NFE2L2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL9837549 | 0.74 | ALDH1A1 (0.36) | NFE2L2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL9838902 | 0.73 | NFE2L2 (0.45) | NFE2L2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL9837608 | 0.71 | CYP19A1 (0.51) | NPC1RAB9ACYP19A1HSD11B1 | |
| SCHEMBL8292382 | 0.70 | MAPT (0.36) | NPC1MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL9837262 | 0.69 | CYP19A1 (0.49) | NPC1RAB9ACYP19A1 | |
| SCHEMBL9839149 | 0.69 | NFE2L2 (0.41) | NFE2L2MAPTALDH1A1PDE4A | |
| SCHEMBL9837903 | 0.68 | CYP19A1 (0.45) | RAB9ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276122-B1 | CYCLOALKYL-SUBSTITUTED 4-AMINOPHENYL HALO DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-08-07 | — | — | EP | claimed |