Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.48 |
| ▸ | HTR3B | O95264 | 4/20 | 0.48 |
| ▸ | HTR3A | P46098 | 4/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415238 | 0.80 | PRKCA (0.59) | KDM4ECYP3A4HSD17B10HTR3EHTR3B | |
| SCHEMBL2421817 | 0.78 | BPTF (0.56) | KDM4ECYP3A4HSD17B10HTR3EHTR3B | |
| SCHEMBL12469440 | 0.75 | PRKCA (0.62) | KDM4ECYP3A4HSD17B10HTR3EHTR3B | |
| SCHEMBL28506643 | 0.75 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1TDP1LMNA | |
| SCHEMBL2869584 | 0.73 | BPTF (0.50) | KDM4ECYP3A4HSD17B10HTR2CHTR2A | |
| SCHEMBL9837631 | 0.72 | HTR3E (0.49) | KDM4ECYP3A4HSD17B10HTR3EHTR3B | |
| SCHEMBL30695563 | 0.72 | ADRB1 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5338538 | 0.72 | ALDH1A1 (0.54) | KDM4ECYP3A4HSD17B10HTR3EHTR3B | |
| SCHEMBL22790262 | 0.71 | HTR3E (0.51) | KDM4ECYP3A4HSD17B10HTR3EHTR3B | |
| SCHEMBL8588025 | 0.71 | HTR3E (0.59) | KDM4ECYP3A4HSD17B10HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |