Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | TPO | P07202 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 3/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784500 | 0.85 | LMNA (0.69) | ALDH1A1KMT2AMAPTLMNAESR1 | |
| SCHEMBL19203480 | 0.85 | LMNA (0.69) | ALDH1A1KMT2AMAPTLMNAESR1 | |
| SCHEMBL9839754 | 0.85 | LMNA (0.69) | ALDH1A1KMT2AMAPTLMNAESR1 | |
| SCHEMBL4621374 | 0.74 | LMNA (0.46) | ALDH1A1LMNAPOLBTK1 | |
| SCHEMBL21277437 | 0.72 | TK1 (0.43) | ALDH1A1LMNAPOLBTK1 | |
| SCHEMBL21277447 | 0.72 | TK1 (0.43) | ALDH1A1LMNAPOLBTK1 | |
| SCHEMBL21345987 | 0.71 | TK1 (0.38) | ALDH1A1LMNAPOLBTK1DHFR | |
| SCHEMBL9839604 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTLMNAESR1 | |
| SCHEMBL114560 | 0.69 | TK1 (0.60) | LMNASMN1; SMN2TK1 | |
| SCHEMBL11875571 | 0.69 | TK1 (0.60) | LMNASMN1; SMN2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075446-A | Synthesis of tetrahydro-2-furylated pyrimidine derivatives | KOREA ADVANCED INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 1991-12-24 | — | — | US | disclosed |