Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375907 | 0.91 | PGR (0.50) | CYP26A1CYP3A4RARAMLYCDMEN1 | |
| SCHEMBL9865366 | 0.85 | MAPT (0.52) | CYP3A4MEN1KMT2ARAB9ALMNA | |
| SCHEMBL9375391 | 0.85 | CYP26A1 (0.52) | CYP26A1CYP3A4RARAMEN1KMT2A | |
| SCHEMBL9376571 | 0.85 | CYP26A1 (0.52) | CYP26A1CYP3A4RARAMEN1KMT2A | |
| SCHEMBL9380149 | 0.84 | PRKAA2 (0.44) | MEN1KMT2ANPC1RAB9AMAPK14 | |
| SCHEMBL9380901 | 0.84 | MEN1 (0.53) | CYP26A1CYP3A4RARAMEN1KMT2A | |
| SCHEMBL9379538 | 0.84 | MEN1 (0.53) | CYP26A1CYP3A4RARAMEN1KMT2A | |
| SCHEMBL9840186 | 0.84 | CYP26A1 (0.51) | CYP26A1CYP3A4RARAMEN1KMT2A | |
| SCHEMBL9375261 | 0.84 | BACE1 (0.55) | CYP26A1CYP3A4RARAMEN1KMT2A | |
| SCHEMBL9374793 | 0.84 | CYP26A1 (0.53) | CYP26A1CYP3A4RARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001986-A1 | N-(DIALKYLOXOPHOSPHINYLALKYL)-LACTAMS, PROCESS FOR PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1991-02-21 | — | — | WO | disclosed |