Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IL18 | Q14116 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840448 | 0.85 | CYP26A1 (0.48) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9313814 | 0.84 | MAOA (0.45) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10585350 | 0.83 | MAOB (0.54) | MAPTALDH1A1KDM4ECA12CA1 | |
| SCHEMBL9314257 | 0.82 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9312451 | 0.82 | RARB (0.52) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9314316 | 0.80 | HSPA9 (0.56) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL6072306 | 0.79 | PGR (0.58) | PGR | |
| SCHEMBL9834136 | 0.78 | NQO2 (0.51) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL9313195 | 0.78 | MAPK14 (0.47) | MEN1KMT2AKDRPGRSMN1; SMN2 | |
| SCHEMBL9375907 | 0.78 | PGR (0.50) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985448-A | Ureidoindoles, pharmaceutical compositions and methods for erythrocyte and thrombocyte aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | claimed |