Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841907 | 0.88 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL9455580 | 0.80 | ALOX5 (0.36) | ALDH1A1SMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL10615233 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL9455668 | 0.73 | GAA (0.39) | ALDH1A1SMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL9827977 | 0.72 | BRAF (0.39) | ACHE | |
| SCHEMBL9122017 | 0.72 | RAB9A (0.42) | ACHEALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9123205 | 0.72 | RAB9A (0.41) | SMN1; SMN2KDM4ERAB9ANPC1GAA | |
| SCHEMBL9120229 | 0.71 | RAB9A (0.49) | ACHEALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9842095 | 0.67 | MKNK1 (0.41) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL9721890 | 0.67 | CA2 (0.48) | ALDH1A1SMN1; SMN2KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254259-A2 | p-Aminophenol derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-01-27 | — | — | EP | claimed |
| US-5059598-A | Antiinflammatory agents; lipoxygenase inhibitors; arthritis; asthma | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1991-10-22 | — | — | US | disclosed |
| US-4868183-A | ANTIINFLAMMATORY, ENZYME INHIBITORS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0254259-A2 | p-Aminophenol derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-01-27 | — | — | EP | disclosed |