Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455580 | 0.91 | ALOX5 (0.36) | ALDH1A1GAATDP1ALOX5PTGS1 | |
| SCHEMBL9841834 | 0.88 | ACHE (0.43) | ALDH1A1GAATDP1ALOX5PTGS1 | |
| SCHEMBL9455668 | 0.83 | GAA (0.39) | ALDH1A1GAATDP1ALOX5PTGS1 | |
| SCHEMBL9123205 | 0.79 | RAB9A (0.41) | GAASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL9120229 | 0.79 | RAB9A (0.49) | ALDH1A1GAAALOX5PTGS1PTGS2 | |
| SCHEMBL9842095 | 0.77 | MKNK1 (0.41) | ALDH1A1GAATDP1ALOX5PTGS1 | |
| SCHEMBL9841885 | 0.77 | ALDH1A1 (0.47) | ALDH1A1GAATDP1ALOX5PTGS1 | |
| SCHEMBL3889851 | 0.77 | SMN1; SMN2 (0.64) | ALDH1A1GAATDP1SMN1; SMN2RAB9A | |
| SCHEMBL3126822 | 0.76 | ALDH1A1 (0.46) | ALDH1A1GAATDP1ALOX5PTGS1 | |
| SCHEMBL18459329 | 0.75 | CA2 (0.61) | ALDH1A1GAATDP1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254259-A2 | p-Aminophenol derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-01-27 | — | — | EP | claimed |
| JP-1025756-A | — | — | None | — | — | JP | disclosed |
| US-5059598-A | Antiinflammatory agents; lipoxygenase inhibitors; arthritis; asthma | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1991-10-22 | — | — | US | disclosed |
| US-4868183-A | ANTIINFLAMMATORY, ENZYME INHIBITORS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0254259-A2 | p-Aminophenol derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-01-27 | — | — | EP | disclosed |