SCHEMBL9842300

SCHEMBL9842300

O=S(=O)(O)c1ccc(-c2cscn2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.42
KDM4A O75164 1/20 0.41
KDM4B O94953 1/20 0.41
KDM5C P41229 1/20 0.41
KDM5B Q9UGL1 1/20 0.41
LMNA P02545 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
CHEK2 O96017 1/20 0.40
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3528459 0.84 CA12 (0.40) KAT6AKDM4AKDM4BKDM5CKDM5B
SCHEMBL28282439 0.82 CA2 (0.52) CA12CA1CA2CA3CA4
SCHEMBL28295968 0.78 KDM4E (0.47) KAT6ALMNACA12CA1CA2
SCHEMBL496710 0.75 LTA4H (0.47) KDM4AKDM4BKDM5CKDM5BLMNA
SCHEMBL3245236 0.75 CHEK2 (0.41) KAT6AKDM4AKDM4BKDM5CKDM5B
SCHEMBL824421 0.73 KDM4E (0.47) LMNACA12CA2CA9TSHR
SCHEMBL27732241 0.73 KAT6A (0.49) KAT6AKDM4AKDM4BKDM5CKDM5B
SCHEMBL7464845 0.71 CHEK2 (0.49) KAT6AKDM4AKDM4BKDM5CKDM5B
SCHEMBL10284703 0.71 KMT2A (0.48) CHEK2TSHRALDH1A1PARP1KDM4E
SCHEMBL31126424 0.71 METAP2 (0.39) KDM4AKDM4BKDM5CKDM5BCHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0452811-A2 Package of photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-10-23 EP disclosed
US-4237214-A P-DIHYDROXYBENZENE DEVELOPING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 US disclosed