Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844781 | 0.85 | DRD2 (0.40) | DRD2TBXA2RMAPTTHRBCFTR | |
| SCHEMBL2072670 | 0.84 | DRD2 (0.40) | DRD2MAPTCFTRTLR7MMP13 | |
| SCHEMBL1386593 | 0.84 | DRD2 (0.40) | DRD2MAPTCFTRTLR7MMP13 | |
| SCHEMBL8997174 | 0.83 | PDE4A (0.38) | MAPTTHRBCFTRTLR7MMP13 | |
| SCHEMBL8997137 | 0.76 | BRD4 (0.36) | MAPTP2RX7 | |
| SCHEMBL9439773 | 0.74 | BCL2L11 (0.34) | THRBCFTRKDM4EALDH1A1MEN1 | |
| SCHEMBL9844763 | 0.70 | NPC1 (0.36) | DRD2MAPTTLR7KDM4EALDH1A1 | |
| SCHEMBL9844745 | 0.69 | MAPT (0.35) | MAPTTLR7KDM4EALDH1A1MEN1 | |
| SCHEMBL8997195 | 0.68 | ATIC (0.35) | MAPTTHRBTLR7EP300MEN1 | |
| SCHEMBL9844783 | 0.67 | EP300 (0.39) | MAPTTHRBEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |