Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844748 | 0.85 | DRD2 (0.39) | DRD2TBXA2RCFTRTLR7MAPT | |
| SCHEMBL9556787 | 0.80 | DRD2 (0.45) | DRD2TBXA2RMAPK8CFTRTLR7 | |
| SCHEMBL2072670 | 0.75 | DRD2 (0.40) | DRD2CFTRTLR7MAPTKDM4E | |
| SCHEMBL1386593 | 0.75 | DRD2 (0.40) | DRD2CFTRTLR7MAPTKDM4E | |
| SCHEMBL8997174 | 0.75 | PDE4A (0.38) | CFTRTLR7MAPTTHRBKDM4E | |
| SCHEMBL9844802 | 0.70 | AGTR1 (0.40) | DRD2TBXA2RTLR7MAPTTHRB | |
| SCHEMBL9844763 | 0.68 | NPC1 (0.36) | DRD2TLR7MAPTKDM4EALDH1A1 | |
| SCHEMBL8997153 | 0.68 | CYP4A11 (0.36) | TLR7MAPTTHRBMEN1KMT2A | |
| SCHEMBL8997195 | 0.67 | ATIC (0.35) | TLR7MAPTTHRBTP53P2RX3 | |
| SCHEMBL9844745 | 0.67 | MAPT (0.35) | TLR7MAPTKDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |