Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 7/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844768 | 0.81 | TBXAS1 (0.39) | PTGER1PTGER4PTGER3PTGER2RARB | |
| SCHEMBL9844766 | 0.81 | KDR (0.46) | EP300LCKKDRTEKSLC16A3 | |
| SCHEMBL27709073 | 0.69 | MBOAT4 (0.50) | TBXAS1EP300ALDH1A1MAPTKMT2A | |
| SCHEMBL9844770 | 0.69 | EP300 (0.49) | EP300ALDH1A1SMN1; SMN2KDR | |
| SCHEMBL133470 | 0.69 | RARB (0.68) | PTGER1PTGER4PTGER3PTGER2RARB | |
| SCHEMBL9101705 | 0.66 | CA12 (0.67) | PTGER1PTGER4PTGER3PTGER2RARB | |
| SCHEMBL371605 | 0.66 | RARB (0.71) | RARBTBXAS1ALDH1A1MEN1RARA | |
| SCHEMBL6139365 | 0.65 | RARB (0.61) | PTGER1PTGER4PTGER3PTGER2RARB | |
| SCHEMBL7825556 | 0.65 | HSD17B10 (0.70) | PTGER1PTGER4PTGER3PTGER2RARB | |
| SCHEMBL28647881 | 0.65 | RARB (0.86) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |