Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844856 | 0.80 | DHFR (0.43) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9844852 | 0.80 | DHFR (0.43) | KDM4EALDH1A1L3MBTL1 | |
| Butane SCHEMBL9844926 | 0.79 | DHFR (0.40) | — | |
| SCHEMBL9844931 | 0.78 | ALDH1A1 (0.39) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL9844747 | 0.73 | CCR6 (0.45) | TLR7ALDH1A1SMN1; SMN2HIF1ADRD2 | |
| SCHEMBL9844768 | 0.70 | TBXAS1 (0.39) | MEN1ALDH1A1MAPTKMT2AMBOAT4 | |
| SCHEMBL27709073 | 0.67 | MBOAT4 (0.50) | ALDH1A1POLBMAPTKMT2ATDP1 | |
| SCHEMBL9046718 | 0.66 | TYMS (0.54) | MBOAT4 | |
| SCHEMBL8801558 | 0.66 | MBOAT4 (0.44) | KDM4EALDH1A1POLBMAPTKMT2A | |
| SCHEMBL1926270 | 0.66 | HDAC1 (0.64) | ALDH1A1NR4A1HDAC1HDAC8PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | claimed |
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |