Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845971 | 0.79 | TDP1 (0.38) | MAP1LC3BALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL9845959 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9845961 | 0.69 | MAP1LC3B (0.34) | MAP1LC3BMAPTLMNAHPGDTSHR | |
| SCHEMBL28002067 | 0.62 | HSD17B1 (0.45) | TP53MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL425308 | 0.61 | POLB (0.58) | MAP1LC3BTP53ALDH1A1MAPK1MAPT | |
| SCHEMBL1781754 | 0.61 | MAP1LC3B (1.00) | MAP1LC3BTP53ALDH1A1MAPK1MAPT | |
| SCHEMBL9845996 | 0.59 | MAPT (0.43) | MAP1LC3BALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL9835316 | 0.57 | ALDH1A1 (0.43) | MAP1LC3BTP53ALDH1A1MAPK1MAPT | |
| SCHEMBL9834910 | 0.57 | KMT2A (0.43) | MAP1LC3BALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL9836877 | 0.57 | MAP1LC3B (0.44) | MAP1LC3BLMNASMN1; SMN2HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414952-A1 | Dithiolane derivatives | NIHON NOHYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |