Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377301 | 0.83 | AHR (0.34) | AHRCTSDBACE1PGRAR | |
| SCHEMBL9372695 | 0.80 | PPIB (0.42) | IDO1CTSDBACE1 | |
| SCHEMBL9372439 | 0.79 | ABCC9 (0.39) | BACE1ABCC9 | |
| SCHEMBL9846796 | 0.78 | AHR (0.33) | AHRIDO1MAPK1PPOX | |
| SCHEMBL1711531 | 0.78 | ALDH1A1 (0.37) | IDO1MAPK1BACE1 | |
| SCHEMBL13172449 | 0.73 | BACE1 (0.42) | CTSDBACE1 | |
| SCHEMBL31619249 | 0.72 | PTGES (0.39) | AHRCTSDBACE1 | |
| SCHEMBL9372171 | 0.71 | F10 (0.35) | CTSDBACE1ABCC9 | |
| SCHEMBL9376811 | 0.71 | PTGS2 (0.34) | MAPK1BACE1 | |
| SCHEMBL9846715 | 0.70 | CTSD (0.36) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |