Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847660 | 0.90 | SMN1; SMN2 (0.34) | MEN1KMT2AKDM4ERECQLNAAA | |
| SCHEMBL6555670 | 0.75 | KDM4E (0.37) | MEN1KMT2AKDM4ERECQLNAAA | |
| SCHEMBL1929102 | 0.73 | KMT2A (0.37) | MEN1KMT2AKDM4ERECQLNAAA | |
| SCHEMBL1929104 | 0.73 | KMT2A (0.37) | MEN1KMT2AKDM4ERECQLNAAA | |
| SCHEMBL9847661 | 0.72 | GPR84 (0.40) | MEN1KMT2AKDM4ERECQLNAAA | |
| SCHEMBL9847657 | 0.72 | NAAA (0.36) | NAAANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9295317 | 0.72 | KDM4E (0.47) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL2655578 | 0.71 | LTA4H (0.37) | NAAATSHR | |
| SCHEMBL6554058 | 0.71 | PTGS2 (0.39) | NAAATSHREPHX2ALDH1A1CYP3A4 | |
| SCHEMBL6277333 | 0.71 | ELANE (0.35) | MEN1KMT2ANPC1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414206-A2 | 2,4,6-Substituted phenol derivatives | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |