Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929102 | 0.80 | KMT2A (0.37) | NAAASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1929104 | 0.80 | KMT2A (0.37) | NAAASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL9847660 | 0.73 | SMN1; SMN2 (0.34) | NAAASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL9296437 | 0.73 | ALDH1A1 (0.35) | NAAASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL9504610 | 0.72 | LTA4H (0.33) | ALDH1A1 | |
| SCHEMBL9847658 | 0.72 | MEN1 (0.38) | NAAASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL6555670 | 0.70 | KDM4E (0.37) | NAAALMNAALDH1A1EPHX1EPHX2 | |
| SCHEMBL9295309 | 0.69 | CTSK (0.35) | LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6554058 | 0.69 | PTGS2 (0.39) | NAAAALDH1A1EPHX1EPHX2HTT | |
| SCHEMBL22013347 | 0.69 | LTA4H (0.30) | SMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414206-A2 | 2,4,6-Substituted phenol derivatives | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |