Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847658 | 0.90 | MEN1 (0.38) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL9847657 | 0.73 | NAAA (0.36) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL9847661 | 0.71 | GPR84 (0.40) | SMN1; SMN2NPC1RAB9ALMNAKDM4E | |
| SCHEMBL6555670 | 0.71 | KDM4E (0.37) | LMNAKDM4EMEN1RECQLKMT2A | |
| SCHEMBL1929104 | 0.70 | KMT2A (0.37) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL10436594 | 0.70 | LMNA (0.52) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL1929102 | 0.70 | KMT2A (0.37) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL9295317 | 0.68 | KDM4E (0.47) | LMNAMAPTKDM4EMEN1RECQL | |
| SCHEMBL2655578 | 0.68 | LTA4H (0.37) | NAAATSHRCYP2C19 | |
| SCHEMBL10434015 | 0.68 | MAPT (0.44) | LMNAMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414206-A2 | 2,4,6-Substituted phenol derivatives | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |