Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847873 | 0.78 | HSD11B1 (0.33) | HSD11B1OPRM1TACR1SLC6A4SLC6A2 | |
| SCHEMBL9847824 | 0.68 | SMN1; SMN2 (0.42) | HSD11B1OPRM1TACR1SLC6A4SLC6A2 | |
| SCHEMBL9847902 | 0.64 | LMNA (0.33) | OPRM1S1PR1 | |
| SCHEMBL9847843 | 0.64 | LMNA (0.38) | HSD11B1OPRM1SLC6A4S1PR1 | |
| SCHEMBL195077 | 0.63 | KDM4E (0.46) | — | |
| SCHEMBL21186738 | 0.62 | ALDH1A1 (0.40) | SLC6A4SLC6A2 | |
| SCHEMBL14126884 | 0.61 | ALDH1A1 (0.32) | — | |
| SCHEMBL16044935 | 0.61 | CA1 (0.38) | — | |
| SCHEMBL9847891 | 0.61 | KDM4E (0.34) | TACR1SLC6A4SLC6A2 | |
| SCHEMBL21481794 | 0.60 | GAA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |