Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847871 | 0.76 | KDM4E (0.35) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL9847821 | 0.71 | KDM4E (0.36) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL25298062 | 0.66 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL10528043 | 0.65 | LMNA (0.43) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL9847904 | 0.64 | HSD11B1 (0.40) | S1PR1OPRM1 | |
| SCHEMBL10530512 | 0.64 | GPR174 (0.38) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL9847843 | 0.63 | LMNA (0.38) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL17494203 | 0.62 | TAS1R3 (0.31) | LMNANPC1MAPK1NPSR1 | |
| SCHEMBL17494234 | 0.62 | LMNA (0.30) | LMNANPC1NPSR1 | |
| SCHEMBL26635353 | 0.62 | ALDH1A1 (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |