Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848394 | 0.86 | ASAH1 (0.61) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL7867488 | 0.81 | MME (0.43) | ALDH1A1 | |
| SCHEMBL7932238 | 0.76 | CTSS (0.42) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11256931 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9150499 | 0.76 | ASAH1 (0.46) | ASAH1ALDH1A1ACER2HDAC8HDAC1 | |
| SCHEMBL27369417 | 0.76 | ITGB3 (0.49) | ASAH1ALDH1A1ACER2 | |
| SCHEMBL7598651 | 0.73 | TSHR (0.47) | ALDH1A1HDAC8HDAC1HDAC6HDAC3 | |
| SCHEMBL9848415 | 0.72 | LMNA (0.53) | ALDH1A1HDAC1LMNASMN1; SMN2 | |
| Sulfuric Acid SCHEMBL9848473 | 0.72 | ITGB3 (0.46) | ASAH1ALDH1A1ACER2HDAC6 | |
| SCHEMBL3579475 | 0.72 | NAALAD2 (0.49) | ASAH1ALDH1A1ACER2UGCGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |