Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869387 | 0.85 | PLAU (0.51) | HSD17B1HSD17B2MAPTNPC1LMNA | |
| SCHEMBL4874528 | 0.81 | CTRC (0.55) | HSD17B1HSD17B2NPC1RAB9ASMO | |
| SCHEMBL7215537 | 0.78 | TARBP2 (0.55) | MAPTNPC1LMNAPOLBALDH1A1 | |
| SCHEMBL29215373 | 0.78 | PLAU (0.49) | HSD17B1HSD17B2MAPTNPC1RAB9A | |
| SCHEMBL9440525 | 0.73 | SIRT2 (0.47) | MAPTNPC1LMNAPOLBALDH1A1 | |
| SCHEMBL7217126 | 0.72 | ENPP3 (0.54) | MAPTNPC1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7221501 | 0.72 | MAPT (0.54) | HSD17B1HSD17B2MAPTNPC1ALDH1A1 | |
| SCHEMBL7221944 | 0.72 | ALDH1A1 (0.54) | MAPTNPC1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL12170948 | 0.72 | NPC1 (0.66) | HSD17B1HSD17B2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL6057368 | 0.72 | LMNA (0.64) | MAPTNPC1LMNAADORA3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440183-A1 | Oxazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-07 | — | — | EP | disclosed |