Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848768 | 0.83 | MEN1 (0.33) | KMT2AMEN1HPGDKDM4EHSD17B10 | |
| SCHEMBL8727685 | 0.67 | ALDH1A1 (0.45) | KMT2AMEN1HPGDGAAALDH1A1 | |
| SCHEMBL9848749 | 0.66 | MAPK1 (0.60) | KMT2AMEN1HPGDKDM4EHSD17B10 | |
| SCHEMBL873778 | 0.65 | CASP3 (0.52) | KMT2AMEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL15478582 | 0.65 | HSD17B10 (0.56) | HPGDKDM4EHSD17B10BRD4GAA | |
| SCHEMBL20979820 | 0.65 | CASP3 (0.50) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL7480856 | 0.62 | SLC6A2 (0.45) | KMT2AKDM4EMAPTHTTNPC1 | |
| SCHEMBL18917449 | 0.61 | ANPEP (0.44) | KMT2AMEN1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL15181275 | 0.59 | MEN1 (0.47) | KMT2AMEN1KDM4EHSD17B10GAA | |
| SCHEMBL25421078 | 0.58 | KMT2A (0.46) | KMT2AMEN1HPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462808-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |