Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848757 | 0.83 | KMT2A (0.36) | MEN1KMT2AHPGDMAPTHTT | |
| SCHEMBL9848755 | 0.70 | MAPK1 (0.56) | MEN1KMT2ARPS6KA2HPGDMAPT | |
| SCHEMBL15181275 | 0.63 | MEN1 (0.47) | MEN1KMT2ARPS6KA2DRD3MAPT | |
| SCHEMBL8727685 | 0.63 | ALDH1A1 (0.45) | MEN1KMT2ARPS6KA2HPGDMAPT | |
| SCHEMBL873778 | 0.62 | CASP3 (0.52) | MEN1KMT2ADRD3HPGDMAPT | |
| SCHEMBL20979820 | 0.61 | CASP3 (0.50) | MEN1KMT2ADRD3MAPTHTT | |
| SCHEMBL9848744 | 0.60 | MAPK1 (0.51) | MEN1KMT2ARPS6KA2DRD3HPGD | |
| SCHEMBL9846149 | 0.60 | LMNA (0.33) | MEN1KMT2ARPS6KA2DRD3HPGD | |
| SCHEMBL9846146 | 0.60 | LMNA (0.33) | MEN1KMT2ARPS6KA2DRD3HPGD | |
| SCHEMBL6520641 | 0.58 | MEN1 (0.46) | MEN1KMT2ADRD3MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462808-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |