Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 12/20 | 0.42 |
| ▸ | CA2 | P00918 | 12/20 | 0.42 |
| ▸ | CA9 | Q16790 | 9/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251610 | 0.86 | CA1 (0.51) | LMNACES2CES1CA1CA2 | |
| SCHEMBL3454583 | 0.79 | TSHR (0.56) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL3862961 | 0.78 | TSHR (0.55) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL28137004 | 0.76 | CES2 (0.50) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL277752 | 0.75 | LMNA (0.52) | LMNACES2CES1CA1CA2 | |
| SCHEMBL10434836 | 0.75 | CA2 (0.51) | LMNACA1CA2CA9CA5A | |
| SCHEMBL10589856 | 0.75 | CA2 (0.51) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL5509813 | 0.74 | LMNA (0.44) | LMNACES2CES1CA1CA2 | |
| SCHEMBL3631033 | 0.74 | BCAT2 (0.51) | LMNACES2CES1CA1CA2 | |
| SCHEMBL31302601 | 0.74 | LMNA (0.46) | LMNACES2CES1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433112-A1 | Modified gangliosides and the functional derivatives thereof | FIDIA S.p.A. (IT) | 1991-06-19 | — | — | EP | disclosed |