Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208466 | 0.69 | CA1 (0.44) | CA1CA2CA7CA9HTR2C | |
| SCHEMBL28886119 | 0.66 | NOS1 (0.42) | MEN1MAPTKMT2A | |
| SCHEMBL8830105 | 0.64 | TTR (0.37) | CA1CA2CA7CA9HTR2C | |
| SCHEMBL21277748 | 0.59 | ADORA2B (0.35) | BACE1CA1CA2CA7CA9 | |
| SCHEMBL28619081 | 0.57 | CA1 (0.40) | CA1CA2CA7CA9HTR2C | |
| SCHEMBL8733810 | 0.57 | CA1 (0.43) | CA1CA2CA7CA9HTR2C | |
| SCHEMBL10716838 | 0.56 | MAOA (0.52) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL13487412 | 0.56 | CA1 (0.52) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL5866470 | 0.56 | CA1 (0.52) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL3375220 | 0.55 | CA2 (0.46) | CA1CA2CA7CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424802-A2 | Tricyclic quinoline antineoplastic agents | ABBOTT LABORATORIES (US) | 1991-05-02 | — | — | EP | disclosed |