Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424998 | 0.80 | KMT2A (0.43) | MMP8SMN1; SMN2ALDH1A1MAPTTP53 | |
| SCHEMBL4272149 | 0.79 | MEN1 (0.45) | MEN1KMT2AOPRM1OPRD1CYP2D6 | |
| SCHEMBL9575042 | 0.79 | MMP8 (0.41) | MMP8SMN1; SMN2ALDH1A1TP53MEN1 | |
| SCHEMBL29582293 | 0.77 | TP53 (0.48) | MMP8SMN1; SMN2ALDH1A1MAPTTP53 | |
| SCHEMBL6006261 | 0.75 | LTA4H (0.50) | SMN1; SMN2LTA4HALDH1A1KDM4EMAPT | |
| SCHEMBL6005401 | 0.75 | LTA4H (0.50) | SMN1; SMN2LTA4HALDH1A1KDM4EMAPT | |
| SCHEMBL557889 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2LTA4HALDH1A1KDM4EMAPT | |
| SCHEMBL11990750 | 0.74 | CHRNB2 (0.54) | MMP8SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7178642 | 0.74 | ALDH1A1 (0.55) | MMP8SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL11315773 | 0.74 | ALOX5 (0.51) | MMP8SMN1; SMN2LTA4HALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |