Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297488 | 0.87 | ALDH1A1 (0.41) | SLC6A2SLC6A4SLC6A3SCN4AMAPT | |
| SCHEMBL9853449 | 0.76 | SRD5A2 (0.40) | BRD4MAPTALDH1A1MEN1THRB | |
| SCHEMBL16167963 | 0.74 | RORC (0.43) | SLC6A4SCN4ABRD4MAPTALDH1A1 | |
| SCHEMBL9853454 | 0.73 | MAPT (0.39) | BRD4MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9853446 | 0.73 | MCHR1 (0.34) | SCN4ABRD4MAPTCYP1A2ALDH1A1 | |
| SCHEMBL27715624 | 0.72 | ALDH1A1 (0.40) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9853451 | 0.71 | SRC (0.41) | BRD4MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6566700 | 0.70 | ALDH1A1 (0.40) | SLC6A2SLC6A3BRD4MAPTCYP2C9 | |
| SCHEMBL9298647 | 0.69 | IDO1 (0.44) | SLC6A2SLC6A4SLC6A3SCN4AALDH1A1 | |
| SCHEMBL9853727 | 0.69 | ESR2 (0.44) | SLC6A2SLC6A4SLC6A3SCN4ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | claimed |
| EP-0446718-A2 | Phenoxy bis-maleimides and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |